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Provider Enrollment and Screening Requirements

The enrollment process includes screening, licensure verification and site visits (if applicable), to ensure that all enrolling providers are in good standing and meet the requirements for which they are seeking enrollment.

  • Be licensed by the appropriate licensing body, certified by the standard-setting agency, and/or other pre-contractual approval processes established by South Carolina Department of Health and Human Services (SCDHHS).
  • Continuously meet South Carolina licensure and/or certification requirements of their respective professions or boards in order to maintain Medicaid enrollment.
  • Comply with all federal and state laws and regulations currently in effect as well as all policies, procedures, and standards required by the Medicaid program. 
  • If eligible, obtain a National Provider Identifier (NPI) and share it with South Carolina Medicaid. 
  • Be enrolled in the South Carolina Medicaid program and receive official notification of enrollment.

Once the provider has been approved for Medicaid enrollment, official notification of enrollment will be sent to the provider.

Online Enrollment

You can enroll using the online application. This process will ensure the security of providers' information and is accessible from any computer that has internet access. The web-based application will enable:

  1. New enrollment for individuals and organizations.
  2. Ordering/referring provider enrollment.
  3. Add a new location(s) to an existing enrollment
  4. Revalidation for individuals and organizations

Online Enrollment

Once you have completed minimal required information, you will receive a Reference ID#. Use this Reference ID# to retrieve and complete an in-process application. The in-process application must be submitted within 30 days. After 30 days, the in-process application will be purged and you must start the enrollment process over and be assigned another Reference ID#.

Complete an online provider enrollment application and agreement and submit any necessary supporting documentation to Provider Enrollment via fax at 803-870-9022. Indicate Reference ID# on all supporting documentation and/or communication in reference to the submitted application. Certain provider types, depending on the type of service provided, will be notified if the provider is required to sign a contractual agreement in addition to the provider enrollment agreement.

Accept the terms and conditions of the online application by electronic signature, indicating the provider’s agreement to the contents of the participation agreement, the Electronic Funds Transfer Agreement, W-9 and Trading Partner Agreement.


When accessing the web application, if either of the two following situations occurs, you will need to make adjustments to your internet browser environment.

  • You correctly enter your NPI and you receive a display message that the NPI is not valid. The first time you may encounter this situation is when you are entering your Individual or Organization information. If you do not encounter this situation until later in the application, please verify that the NPI has been entered correctly.
  • Your view of the page shows an excessive amount of spacing between entry fields requiring an unusual amount of page scrolling. If you encounter this situation, it will occur after you select "Begin a New Enrollment". The next page displayed will require you to select either "New Enrollment" or "Add a Location". When you select either button, the “Enroll Now” button in the bottom right-hand corner should not disappear from your immediate page view. If the "Enroll Now" button is not viewable without scrolling, you will need to complete the steps listed below to solve the problem.

The issue causing either of these situations is the "compatibility view" settings of your internet browser. Completing the following steps will allow you to use the Provider Enrollment web application in the manner intended.

  1. Close your current web application by selecting "Exit Enrollment" in the upper right-hand corner of the application.
  2. Select “OK” to the pop-up message advising you that you will be exiting the application and any entered data will be lost.
  3. In the Menu bar of your internet browser, select "Tools".
  4. Selecting “Tools” will display a drop-down list of your browser settings.
  5. In the drop-down list, select the "Compatibility View Settings" entry.
  6. Confirm that "" does not appear in the text box labeled "Websites you’ve added to Compatibility View".
  7. Should the entry appear in the text box, click on the "" entry.
  8. Click the "Remove" button.
  9. Confirm that "" is removed from the text box.
  10. Select "Close" to close the window.
  11. You are now ready to once again begin your new enrollment application.

Web Application System Requirements

The interactive web application works with the following:

  • Internet Explorer: Version 8, Version 9
  • Firefox: Version 13, Version 14, Version 15, Version 16
  • Chrome: Version 23.0.1271.64
  • Safari: Version 6.0.1